The,nature,glutathione,Half,th health The nature of glutathione
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Half of the ³-L-glutamyl-L phthalatecysteine phthalocyanine glycine by its chemical name, the English name is L-Glutathione.Glutathione is isolated from the yeast in1888; in 1921, scientists extracted crystallized and conceived its structure;elucidate its chemical structure and synthesis team in 1935, Enzymaticsynthesis of glutathione mechanismexplore in 1953; seventies of the lastcentury, further study of the chemical synthesis of glutathione, focused onprocess improvements; eighties of the last century, due to the development ofgenetic engineering technology, glutathionesupplier began to study the production of glutathione bacteriaand(enzyme) production of glutathione immobilized.The relative molecular weight of glutathioneis 307.33, the melting point is 189 to 193 ° C, the crystal was colorless andtransparent elongated granular, the isoelectric point is 5.93. It is soluble inwater, dilute alcohols, ammonia, and dimethylformamide and not soluble inalcohol, ether and acetone. Glutathione solid is more stable, with water in theair is easily oxidized, and the two molecules also prototype active mercaptoglutathione disulfide oxidative condensation, i.e. the oxidized glutathione.Expressed in ionic form, can be seen as the missing electron oxidation (SHcompound is weakly acidic, H + SH group to). This reaction is reversible, soglutathione has redox role. Oxidized glutathione (GSH) and reduced glutathionewas having a physiological activity can play an important physiological need torestore oxidized glutathione vivo function. Therefore, when extractingglutathione can be added substances in solution which having a strong reducing suchas vitamin C, etc. when there is a strongly reducing material can protectglutathione is not easy to be oxidized.Glutathione in the distribution of plantsand animals, glutathione nature is abundant in many plants and animals. Veryhigh levels in the baker's yeast, wheat germ and animal liver is 100 = 1000mg/100g, 26 = 34mg/100gcontaining in human blood, with blood containing 58 = 73mg/100g , pig blood containing 10 = 15mg / 100g, tomatoes, pineapple, cucumber, content is alsohigher (12 = 33mg/100g), sweet potatoes, green beansprouts, onions, mushrooms, low levels (0.06 = 0.7mg/100g).The glutathione structure containing a reactive sulfhydryl-SH, the easilyoxidized deoxidation, the specific structure makes it become the main bodyradical scavengers. The body metabolism of many free radicals can damage cellmembranes, invasion of macromolecules of life, promote aging body and generateinduced tumors or atherosclerosis. As a cosmetic raw material, glutathione canscavenge free radicals play a strong protective effect on anti-aging. Forexample, when cells generate a small amount of H2O2 and glutathione in the roleof glutathione peroxidase will reduce H2O2 to H2O, and itself is oxidized toGSSG, GSSG by glutathione in the liver and red blood cells, glutathione underthe role of reductase catalytic, accept H reduced to glutathione, a freeradical reactions to be sustained. Glutathione is a very special amino acidderivatives, and mercapto group-containing tripeptide, so it plays an importantrole in vivo.Source:http://www.cosprm.com
The,nature,glutathione,Half,th