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According to a recent study, psychedelic mushrooms and newCanada drugs may lead to new mannersof treating depression. "Psychedelics are thought of as 'mind-expanding'drugs, so it has commonly been assumed that they work by increasing brainactivity, but surprisingly, we found that psilocybin actually caused activityto decrease in areas that have the densest connections with other areas," accordingto David Nutt, who's with the Department of Medicine at Imperial CollegeLondon, was the senior author of both of the new studies. "These hubsconstrain our experience of the world and keep it orderly. We now know thatdeactivating these regions leads to a state in which the world is experiencedas strange." The impact of psilocybin reported by the studyparticipants -- such as seeing "geometric" patterns, experiencing analtered sense of time and space, and unusual physical sensations -- correlatedwith a decreased flow of oxygen and blood to parts in the brain's posteriorcingulate cortex and medial prefrontal cortex (mPFC), the study authors said. It's thought that the posterior cingulate cortex plays arole in consciousness and self-identity. Research has shown the medialprefrontal cortex to be especially active in people struggling with depression,so psilocybin's effect on this area of the brain could be responsible for someof the antidepressant effects reported in previous research, the study authorssaid. "Psilocybin was used extensively in psychotherapy inthe 1950s, but the biological rationale for its use has not been properlyinvestigated until now. Our findings support the idea that psilocybinfacilitates access to personal memories and emotions," Dr. Robin Carhart-Harris,from the Department of Medicine at Imperial College London, and first author ofboth studies, said in the news release. For the meantime, it is recommended to buy Celexa onlineforthe treatment of symptoms of patients with depression. "Previous studies have suggested that psilocybin canimprove people's sense of emotional well-being and even reduce depression inpeople with anxiety. This is consistent with our finding that psilocybindecreases mPFC activity, as many effective depression treatments do. Theeffects need to be investigated further and ours was only a small study, but weare interested in exploring psilocybin's potential as a therapeutic tool,"Carhart-Harris added. With this, it ispossible to design meds with this newly discovered remedy and have themavailable at various Canadian pharmacies. Depression is a state of low mood and aversion toactivity that can affect a person's thoughts, behavior, feelings and physicalwell-being. Depressed people may feel sad, anxious, empty, hopeless, helpless,worthless, guilty, irritable, or restless. They may lose interest in activitiesthat once were pleasurable; experience loss of appetite or overeating, haveproblems concentrating, remembering details, or making decisions; and maycontemplate or attempt suicide. Insomnia, excessive sleeping, fatigue, loss ofenergy, or aches, pains or digestive problems that are resistant to treatmentmay be present. Depressed mood is not necessarily a psychiatricdisorder. It is a normal reaction to certain life events, a symptom of somemedical conditions, and a side effect of some medical treatments. Depressedmood is also a primary or associated feature of certain psychiatric syndromessuch as clinical depression. A number of psychiatric syndromes feature depressedmood as a main symptom. The mood disorders are a group of disorders consideredto be primary disturbances of mood. These include major depressive disorder(MDD), commonly called major depression or clinical depression, where a personhas at least two weeks of depressed mood or a loss of interest or pleasure innearly all activities; and dysthymia, a state of chronic depressed mood, thesymptoms of which do not meet the severity of a major depressive episode.Another mood disorder, bipolar disorder, features one or more episodes ofabnormally elevated energy levels, cognition and mood, but may also involve oneor more depressive episodes.
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