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Asidefrom generic Neurontin 300mg, which affectschemicals and nerves in the body that are involved in the cause of seizures andsome types of pain, a new study in mice suggests that scientists may someday beable to treat nerve pain by transplanting embryonic nerve cells to restore abroken nervous system. "Nothingthat gets rid of the pain works for a long period of time," said studyco-author Allan Basbaum, chair of the department of anatomy at the Universityof California, San Francisco. "The problem is that even if drugs sort ofwork, they work everywhere in the body and inevitably have adverse side effectslike sedation and mental clouding." "Nervepain can strike a variety of types of patients, from those who have hadshingles or undergone chemotherapy to those with diabetes. Scientists thinkcertain nerve cells become damaged or lost, and lose the ability to regulatethe pain signals that go to the brain," Basbaum said. "Someof the cells developed into neurons. Within four weeks, the mice lost theirhypersensitivity." Basbaum said, "The findings show unequivocallythat the cells integrated into the nervous system of the mice." If this isfound feasible in humans, to buyNeurontincheap will no longerbe an option. "Thenext step is to inject human embryonic nerve cells into mice that aregenetically engineered to not reject human tissue. We want to do the groundworkto learn how to handle human cells," Basbaum said. "Theultimate goal is to test the treatment in humans," Basbaum said. "Butif the cells don't integrate as they do in the mouse, or the cells don'tsurvive, then it doesn't work." Hesaid, "the potential cost of the procedure isn't known. Any work with humanembryonic cells could create controversy because they're derived from humanembryos. However, scientists are trying to find alternative ways to develop thecells." LauraStone, an assistant professor at McGill University's Alan Edwards Center forResearch on Pain in Montreal, praised the study. "Theresearch demonstrates that transplantation of cells into the spinal cord couldbe used as a strategy perhaps not only in chronic pain but in spinal cordinjury or other neurodegenerative disorders," she said. "Still,the treatment that worked in mice might not work in humans. Even if it does, anavailable treatment for people would be many, many years away," Stoneadded. "Inthe big picture, however, there has been an enormous amount of progress in thelast 20 years on understanding basic mechanisms underlying chronic pain ingeneral and neuropathic pain in particular," Stone said. "We as afield have identified many new possible drug targets that were unknown just afew years ago." Canada drug availablewill continue to maintain their established dedication in carrying out missionsto progress in the health arena. Organ transplantation is themoving of an organ from one body to another or from a donor site on thepatient's own body, for the purpose of replacing the recipient's damaged orabsent organ. The emerging field of regenerative medicine is allowingscientists and engineers to create organs to be re-grown from the patient's owncells (stem cells, or cells extracted from the failing organs). Organs and/ortissues that are transplanted within the same person's body are calledautografts. Transplants that are recently performed between two subjects of thesame species are called allografts. Allografts can either be from a living orcadaveric source.
Canada,Drug,Back-ups,New,Nerve