Canada,Pharmacy,Review,Ovarian health Canada Pharmacy Review on Ovarian Tumor Fighting Drugs
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Frenchresearchers report that a targeted therapy already enlisted in the fightagainst colorectal cancer, lung cancer and kidney cancer may also have a roleto play in recalcitrant ovarian cancer. Gemzarinjection is one of the oncology drugs highlighted to have successfullyhelped ovarian cancer patients. "Thisis the first time that there has been a significant advance in thesedifficult-to-treat patients," said study author Dr. Eric Pujade-Lauraine,head of medical oncology at Hopitaux Universitaires Paris-Centre siteHotel-Dieu, in France. "These data open a new era for biologics whenchemotherapy is not doing its job in recurrent ovarian cancer." Accordingto Dr. Elizabeth Poynor, a gynecologic oncologist and pelvic surgeon with LenoxHill Hospital in New York City, some physicians are already using Avastin inthese settings. Thistrial, she said, "provides further evidence of benefit." Avastinwas the first in a class of drugs developed to inhibit angiogenesis, or theformation of blood vessels, which helps fuel a tumor's growth.Thisstudy is actually the fourth phase 3 trial finding some benefit to usingAvastin for different stages of ovarian cancer, said Dr. Jamal Rahaman, anassociate clinical professor in the division of gynecologic oncology at MountSinai School of Medicine, in New York City. "Itmay not seem like three months is spectacular progression-free survival, butthis suggests that angiogenesis drugs probably have a real role to play [inovarian cancer]," Poynor explained. "We're defining how to useAvastin in ovarian cancer." "Theywere picking out the very, very best patients here, which does not necessarilytranslate to all patients with ovarian cancer," said Dr. Jay Brooks,chairman of hematology/oncology at Ochsner Health System in Baton Rouge, La. Thechallenge now is to select those patients for whom Avastin would be mostbeneficial, said Rahaman. "Thecommunity is trying to figure out if we can identify those women who would getthe most benefit so we can justify the cost and the increased sideeffects," he said. Ayear's worth of Avastin runs about $100,000 a year in the United States, headded. "Thisis very early research," Brooks said. "With time, as the data matures,we will begin to answer the question as to whether this drug is reallyworthwhile." While the research ison-going, to buy Gemzaronline is considered one of the bestalternatives. Ovarian cancer is a cancerous growth arising from theovary. Symptoms are frequently very subtle early on and may include: bloating,pelvic pain, difficulty eating and frequent urination, and are easily confusedwith other illnesses. Most (more than 90%) ovarian cancers are classified as"epithelial" and are believed to arise from the surface (epithelium)of the ovary. However, some evidence suggests that the fallopian tube couldalso be the source of some ovarian cancers. Since the ovaries and tubes areclosely related to each other, it is thought that these fallopian cancer cellscan mimic ovarian cancer. Other types may arise from the egg cells (germ celltumor) or supporting cells. These cancers are grouped into the category ofgynecologic cancer. Signs and symptoms of ovariancancer are frequently absent early on and when they exist they may be subtle.In most cases, the symptoms persist for several months before being recognizedand diagnosed. Most women with ovarian cancer report one or more symptoms suchas abdominal pain or discomfort, an abdominal mass, bloating, back pain,urinary urgency, constipation, tiredness and a range of other non-specificsymptoms, as well as more specific symptoms such as pelvic pain, abnormalvaginal bleeding or involuntary weight loss. There can be a build-up of fluid(ascites) in the abdominal cavity.
Canada,Pharmacy,Review,Ovarian