Canadian,Pharmacy,Warns,Recipi health Canadian Pharmacy Warns Recipients of Smokers Lungs for Tra
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Should the lungs of smokers beincluded in lung transplants? A new study suggests their inclusion may bewarranted. The issue raised is whether to continue with Generic Alimta for medication or consider lung transplant even ifthe donor is a smoker. The issue is not just aBritish one -- speaking to the Associated Press, Dr. Normam Edelman,chief medical officer for the American Lung Association, said smokers' lungsare also used for transplant in the United States, although he did not havedata on how common the practice might be. But the bottom line from thenew study is that "patients awaiting lung transplantation in the U.K. arelikely to survive longer if they are willing to accept lungs from any suitabledonor, irrespective of smoking history," lead author Dr. Robert Bonser, ofthe Queen Elizabeth Hospital in Birmingham and the University of Birmingham,said in a journal news release. "Donors with a positive smoking historyprovide nearly 40 percent of the lungs available for transplantation [in theU.K.] Rejection of this donor-organ resource would increase waiting-listmortality and is ill-advised." "Although lungs from suchdonors are associated with worse outcomes, the individual probability ofsurvival is greater if they are accepted than if they are declined and thepatient chooses to wait for a potential transplant from a donor with a negativesmoking history," the authors wrote. "This situation should be fullyexplained to and discussed with patients who are accepted for lungtransplantation." One expert in the UnitedStates said the study "raises a few issues." Dr. Len Horovitz, pulmonaryspecialist at Lenox Hill Hospital in New York City, said that "becausemany patients may die awaiting transplant, one might argue that a lung damagedby smoking (not severely) would be better than no functioning lung at all. Butlungs of smokers may be mild or moderately damaged (COPD), and also carry therisk of lung cancer, especially with post operative chronic use of immunesuppressors. Nevertheless, in a dying patient, the prolongation of life --however long that may be -- [and] the benefit is clear." Although these findings haveclear implications for the United Kingdom, it "is important to realizethat the relation between risk of dying on the waiting list and the benefit ofaccepting a transplant from a donor with a substantial smoking history can varyby country and center," Dr. Shaf Keshavjee and Dr. Marcelo Cypel of the TorontoLung Transplant Program of the University Health Network in Canada, wrote in anaccompanying commentary in the journal. This is regarded very important if to buy Alimta online could no longerwithstand the condition of the patient. Smoking, particularly of cigarettes, is by far the main contributor tolung cancer. Cigarette smoke contains over 60 known carcinogens, includingradioisotopes from the radon decay sequence, nitrosamine, and benzopyrene.Additionally, nicotine appears to depress the immune response to malignantgrowths in exposed tissue. Across the developed world, 91% of lung cancerdeaths in men during the year 2000 were attributed to smoking (71% for women).In the United States, smoking is estimated to account for 87% of lung cancercases (90% in men and 85% in women). Among male smokers, the lifetime risk ofdeveloping lung cancer is 17.2%; among female smokers, the risk is 11.6%. Thisrisk is significantly lower in nonsmokers: 1.3% in men and 1.4% in women.
Canadian,Pharmacy,Warns,Recipi