Canadian,Pharmacies,Report,New health Canadian Pharmacies Report New Heart Drug Soon to be Release
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An experimental medicine,omecamtiv mecarbil, which is being manufactured by Cytokinetics Inc. in SanFrancisco may give an alternative to existing treatments that will preventpatients to buy Plavix. "It improves heartfunction in a completely new and unique manner," according to Dr. John R.Teerlink, a cardiologist at the San Francisco Veterans Affairs Medical Centerand author of one of the recent studies. "The drug directlyincreases the activation of certain heart muscle proteins, effectivelyrecruiting 'more hands on the rope' with each heartbeat," he stated."By improving the efficiency and performance of the heart, it is our hopethat patients with heart failure will actually feel better with fewer symptomsof fatigue and shortness of breath, and perhaps even live longer," he added. The currently available heartfailure drugs, like generic Plavix,indirectly boost heart performance, and can bring hazardous, even lethal, heartrhythm irregularities, Teerlink said. "These drugs are 'necessary evils'because they are the only currently available pharmacologic means to increaseheart function," he conveyed. "It is a promising drug,but we have been down this road before," he said. "When you have heartfailure, the pumping action of the heart is weak, so not enough blood gets tothe body, and you feel short of breath, sleep a lot and your kidneys don'twork," Dr. Ronald Zolty explained, director of the heart failure programat the Albert Einstein College of Medicine in New York City. "Existing drugs doimprove the squeeze, but they also increase mortality," he stated. "The major problem weface in treating heart failure is how can we make the heart squeezeharder," Dr. Michele Hamilton said, director of the heart failure programat Cedars-Sinai Heart Institute in Los Angeles. "To date, no medications have proveneffective or safe, and as a result, doctors focus on getting rid of excessfluid buildup and reducing stress on the heart," she said. "Medications that makethe heart squeeze harder put more stress on the heart, and the patients diesooner. It is akin to whipping a tired horse as it goes uphill," she conveyed. "It's great to see a newmedication being tested and developed," Hamilton said. But, "we arefar away from the finish line." Nevertheless, this will soon be availablein your nearest Canadian pharmacies. The heart is a myogenic muscular organ found in allanimals with a circulatory system (including all vertebrates), which pumpsblood throughout the blood vessels by repeated, rhythmic contractions. The termcardiac (as in cardiology) means "related to the heart" and comesfrom the Greek º±Á´¹¬, kardia, for "heart". The vertebrate heart is principally composed of cardiac muscleand connective tissue. Cardiac muscle is an involuntary striated muscle tissuefound only in this organ and responsible for the ability of the heart to pumpblood. The average human heart, beating at 72 beats per minute, will beatapproximately 2.5 billion times during an average 66 year lifespan. It weighsapproximately 250 to 300 grams (9 to 11 oz) in females and 300 to 350 grams (11to 12 oz) in males. In invertebrates that possess a circulatory system, theheart is typically a tube or small sac and pumps fluid that contains water andnutrients such as proteins, fats, and sugars. In insects, the "heart"is often called the dorsal tube and insect "blood" is almost alwaysnot oxygenated since they usually respirate (breathe) directly from their body surfaces(internal and external) to air. However, the hearts of some other arthropods(including spiders and crustaceans such as crabs and shrimp) and some otheranimals pump hemolymph, which contains the copper-based protein hemocyanin asan oxygen transporter similar to the iron-based hemoglobin in red blood cellsfound in vertebrates. The mammalian heart is derivedfrom embryonic mesoderm germ-layer cells that differentiate after gastrulationinto mesothelium, endothelium, and myocardium. Mesothelial pericardium formsthe outer lining of the heart. The inner lining of the heart, lymphatic andblood vessels, develop from endothelium. Heart muscle is termed myocardium.
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