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The extract of a specific subspecies of rhubarb root, called Siberian rhubarb root has been used in Germany to provide effective relief of hot flashes, sweats and other menopausal related complaints since 1993.Four different clinical studies published in recognized medical journals (Menopause (2006, 2007 and Alternative Therapies in Health and Medicine 2008, 2009) have now been published on the herbal extract. These studies confirm the benefits of Siberian rhubarb root extract (called ERr 731 by researchers). The herb has only recently become available in the United States (2009).Here are summaries of the four clinical studies, all showing Siberian rhubarb root extract to be very effective in the relief of hot flashes and night sweats.Clinical study #1 (reported in Menopause, 2006):109 symptomatic perimenopausal women received either ERr731 or placebo. After 4 weeks the group receiving ERr731 showed significant improvement in the 11 common menopausal complaints on the Menopause Rating Scale.at four weeks there was a significant lessening of the severity and number of hot flasheswomen taking ERr731 reported significantly less anxiety and improved moodsat 12 weeks the group taking ERr731 showed significant improvement in vasomotor [hot flashes], psychosocial [anxiety, mood, depression], physical and sexual scores on the Menopause-Specific Quality of Life assessment.Clinical Study #2 (reported in Menopause(2), 2009):This study continued to follow the results experienced by subjects in Clinical Study #1 above. 80 of the subjects in study #1 were followed for an additional 108 weeks (for more than two years). The study showed that long term use of ERr731 resulted in sustained relief of menopausal complaints. By the end of the study women taking ERr731 reported an average of not more than 2 slight hot flashes per day.Clinical Study #3 (reported in Alternative Therapies in Health and Medicine(3), 2008):In this study 252 perimenopausal and menopausal women being seen through 70 gynecological practices were given ERr731 for 6 months. Women received varied doses of ERr731, most receiving one tablet daily. The study found that most of the women in the study experienced significant relief of menopausal symptoms taking just one tablet daily. Symptoms were evaluated using the Menopause Rating Scale. The average total score dropped from 14.5 points to 6.5 points, or more than 50%.Clinical Study #4 (reported in Alternative Therapies in Health and Medicine(4), 2009):In this study 112 perimenopausal women with symptomatic complaints were given one tablet of ERr731 daily. After 12 weeks the women experienced a significant drop in the number of hot flashes, from a median of 12 to 2. Women with more severe hot flashes tended to experience the greatest benefit from ERr731. This drop in the number of hot flashes is comparable to that reported for women taking an ultra low dose of hormone replacement therapy. The women taking ERr731 in this study also experienced improvement in the 10 other categories of the Menopause Rating Scale as well. The 11 categories of the Menopause Rating Scale are:hot flushes and sweatingheart complaintssleep disturbancesdepressive moodirritabilityanxietyphysical and mental exhaustionsexual problemsurinary tract complaintsvaginal drynessjoint and muscle problemsRecent studies of hormone replacement therapy (HRT) have raised even more questions about the safety of traditional hormone prescriptions. HRT is now associated with increased risk for breast cancer and heart disease.Siberian rhubarb root extract to the rescue. Fortunately clinical studies are confirming the benefits of a natural herbal remedy for hot flashes, sweats and other menopausal symptoms that is safe.Information on how to purchase Siberian rhubarb root extract can be found here.Siberian rhubarb root extract is easy and convenient to take. The clinical studies referred to above found that 4 milligrams daily of the extract provided the reported benefits. This is just one small tablet which is taken daily in the morning with breakfast for long lasting hot flash natural and safe relief.In clinical studies of most hot flash natural remedies like soy, flax seeds and black cohosh, relief of hot flashes and sweats has not been consistent. At best hot flashes have been reduced a maximum of 45%. As a hot flash natural remedy which reduces hot flashes and night sweats by 72%, Siberian rhubarb root extract far exceeds the benefit of other herbal remedies.