The,Fight,against,Arthritis,Ex health The Fight against Arthritis

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Except from the two things we can be certain of in life: death and taxes,there is a third most of us can count on, which is arthritis.It effects nearly 70% - 80% of the population over the age of fifty.The most common type is called: osteoarthritis or degenerativearthritis, which  is an inflammatory disease.Symptoms are:early morning stiffness, swollen joints and joint painover the entire body. In an advanced state, it can cause significantpain, discomfort and even disability.Osteoarthritis is caused by degeneration of the cartilage in the jointsor the lining of the joints. The cartilage can worn out completely bymechanical stress, caused by excessive weight, trauma or activity.The end of our bones is covered by articular cartilage. Our jointshave additional cartilage that act like a shock absorber betweenthe bones. Old cartilage breaks down, while new cartilage is formed.This process has to be kept in balance in order to keep healthy  joints.There are several causes of inflammation in our joints.The cytokins are among the leading causes. These are proteinswho carry messages between cells and regulate immunity andinflamation. Two of the most important ones are:tumor necrosis factor alpha (TNF- a) and interleukin one beta (IL-B).They are highly concentrated in the joints of people with osteoarthritis. The second group are the proteases, enzymes that cause thebreakdown of proteins. Proteases are under control of the cytokines.Some have anti-inflammatory   qualities and some have pro-inflammatory qualities, which are in the majority with arthritis.The third group are the phagocytes (or neutrophils), which areattracted to the inflamed joint while trying to clear this reaction andto prevent damage to the cartilage and lining of the joint.But this inflammatory response can actually cause more inflammationto the joint. The pressure caused by our weight on our joints block the bloodsupply to the cartilage. This phenomenon is called Ischemia.When we take our weight of the joint, the pressure is reduced andblood returns back to the cartilage, this is called reperfusion.This process causes excessive production of free radicals.These free radicals put heavy weight on the antioxidant defencesystem and cause oxidative stress and consequently damage tothe cartilage and synovial lining of the joint. When the body can't rebuild cartilage fast enough, deterioration occurs.Rheumatoid arthritis is another form of arthritis. This is anautoimmune disease. When our immune system starts to attackthe cartilage and the synovial lining of the joint, an inflammatoryprocess starts to destroy healthy tissue.This not only createexcessive free radicals, but also attracts TNF-a cytokines. Production of free radicals is five times higher in patients withrheumatoid arthritis than in patients with osteoarthritis and causesgreater oxidative stress and damage to the joints.This damaging effect can cause severe pain an deformity.When considering traditional treatments, it is important to knowthe real causes of these diseases.The traditional treatment of both types of arthritis, callednonsteroidal anti-inflammatories (NSAIDS) and aspirin, causedsevere side effects, like stomach ulcers and upper -gastrointestinal bleeding (GI). Because of this, pharmaceutical companies developed a groupof new NSAIDS , called COX 2 inhibitors, which significallyreduced GI. Unfortunately, these have side effects as well, likebowel perforation and upper GI bleeds, but less frequent.These drugs mainly reduces the pain but do nothing about thebasic cause of the disease, which is oxidative stress.Apart from a well balanced, high quality mineral and antioxidant supplement patients suffering from arthritis should also takeglucosamine sulfate, which is one of the basic nutrients for thesynthesis of cartilage. It is a simple amino sugar and gives the cartilage its elasticity.Unlike NSAIDS and aspirin, which only reduces the pain,glucosamine helps to rebuild the damaged cartilage.In 1999 a large study revealed that glucosamine not only reduced the pain and inflammation of arthritis, but actuallystopped the deterioration of the cartilage and even showedevedence of cartilage regrowth, without any side effects.Another important advantage was that the pain didn't returnfor weeks and even months!Chondrotin sulfate is often combined with glucosamine in orderto make the cartilage more pliable and spongy, as chondrotinattracts water into the cartilage. Without it, the cartilage becomesdrier and more fragile.Cellular nutrition is the key to prevent arthritis. This is anotherarea in which nutritional supplements work together with yourbody to maintain or regain your health.