Mesothelioma,Diagnosis-What,th health Mesothelioma Diagnosis-What is the role of Tumor Markers?
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What is a Tumor Marker?Tumor markers are best described as substances produced by tumor cells(or sometimes other cells) in the body in response to certain cancerousand non-cancerous conditions. They are usually found in the blood,urine, or tissue of patients. Using tumor markers to diagnose cancercan be difficult because tumor marker levels are not altered in allpatients with cancer. Even levels of the same tumor marker can bealtered in more than one type of cancer. Some of these substances canalso found at elevated levels when other non-cancerous diseases arepresent. What are Tumor Markers Used For?1- Early DetectionTumor markers are a good starting point in the detection of cancer.While an elevated level of a particular tumor marker does notnecessarily indicate the definite presence of cancer, it does indicatethe need for further testing. The additional tests may include abiopsy, CT scan, or MRI.2- Monitoring of Response to treatmentIn addition to being used for the diagnosis of cancer, tumor markerscan also be measured to determine how a patient is responding totreatment. Marker levels will often be measured before treatment beginsto determine the correct course of action when addressing the cancer.Tumor marker levels can further be used to determine whether a patienthas suffered a recurrence of their cancer.3-Screening for mesotheliomaThis is a process during which a cancer can be detected before symptomsare evident. Many researchers believe tumor markers aren't sensitiveenough to be used for screening, yet one tumor marker, theprostate-specific antigen (PSA), has been used in the screening ofprostate cancer among men for several years and has shown much success.However, an elevated PSA level does not necessarily indicate cancer,but does indicate the need for further testing.Tumor Markers That Are Used To Diagnose MesotheliomaA test approved recently by the Food and Drug Administration (FDA) isnow being used to screen for mesothelioma among individuals at risk forthe disease. Because mesothelioma symptoms do not usually surface untilafter a long latency period, this new test, called Mesomark blood test,could make the difference between life and death for mesotheliomapatients. Mesomark measures the amount of Soluble Mesothelin-Related Peptides(SMRP) in human serum. SMRP is a tumor marker that is produced bymesothelioma cells. This tumor marker may be elevated in mesotheliomapatients even in the very early stages of the disease. Article Tags: Tumor Markers, Tumor Marker, Marker Levels
Mesothelioma,Diagnosis-What,th