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Cretinism is a circumstance of seriously stunted physiological and psychological increase payable to raw inborn inadequacy of thyroid hormones. Cretins have dwarfed bodies, with curvature of the backbone and pendulous stomach. Their limbs are distorted, their features are crude, and their hair is rough and scanty. Mental growth is retarded throughout living. Congenital hypothyroidism can be indigenous, hereditary, or intermittent. Neurological disability may be balmy, with reduced muscle color and coordination, or then serious that the individual cannot support or walking. Cognitive disability may too drift from balmy to then serious. The individual is nonverbal and reliant on others for fundamental maintenance. Thought and reflexes are slower. Other signs may include thickened rind and a jutting stomach. Sporadic and hereditary cretinism results from irregular growth or role of the fetal thyroid gland. Treatment of adult cretins with thyroxine or thyroid distill results in some advance; earlier handling in infancy results in remedy of the disease and natural growth of the person, provided the handling is continued throughout living. Treatment is sometimes begun prenatally, for example, when a mother suffers from serious goiter, a disease of the thyroid. T4 tablets are mostly crushed and mixed with bosom milk, formula or water. The medicine should not be mixed with any formulas containing iron or soya as these substances may change the bioavailability of thyroid hormone from the intestine.
Complete,Information,Cretinism